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ACS Chem Neurosci 15:30443052
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In a two-year randomised, placebo-controlled trial in adults aged 60 to 81, fat-free mass rose by 1.1 kg while the placebo group lost 0.5 kg but the added lean mass did not produce measurable gains in strength or physical function, and fasting blood glucose rose while insulin sensitivity fell (Nass et al., Annals of Internal Medicine , 2008)
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